GBA Webinar with Tijana Radivojevic & Douglas Densmore

2021 Global Biofoundries Alliance Webinar Series January 27, 2021 1-2PM PST/4-5PM EST

Please join us for the first GBA webinar of 2021! Register in advance for this webinar by clicking here.

Tijana Radivojevic Data Scientist DOE Agile BioFoundry

Automated Recommendation Tool (ART) – Design of Experiments via probabilistic predictive modeling Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or anticancer drugs. However, traditional synthetic biology approaches involve ad-hoc engineering practices, which lead to long development times. We present the Automated Recommendation Tool (ART), a tool that leverages machine learning and probabilistic modeling techniques to guide synthetic biology in a systematic fashion, without the need for a full mechanistic understanding of the biological system. ART provides a set of recommendations for the next engineering cycle, alongside probabilistic predictions of their outcomes. It can be used as a python library or through a web-based graphical frontend that does not require coding expertise.

Douglas Densmore Associate Professor DAMP Lab DAMP Lab: Services, Workflows, and Infrastructure for Remote Synthetic Biology

In this talk I will outline the current state of the “Design, Automation, Manufacturing, and Prototyping” (DAMP) Lab at Boston University. This includes a software infrastructure for the execution of numerous experimental microbiology services, the analysis of the performance of these services, and a direct connection to the physical fabrication of low-cost microfluidics from high-level specifications. I will provide insight into several engagements that the DAMP Lab has been involved in as well as talk about how the DAMP Lab can contribute more to the Global BioFoundry Alliance (GBA) in 2021 and beyond.